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Related Experiment Video

Updated: May 11, 2026

Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines
12:06

Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines

Published on: November 25, 2017

Biomedical applications of mannan conjugates.

Ariba Khan1, Jai Vengurlekar1, Amol Gholap2

  • 1Institute of Chemical Technology, Marathwada Campus, Jalna, Maharashtra 431203, India.

Drug Discovery Today
|May 9, 2026
PubMed
Summary
This summary is machine-generated.

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Mannans, natural polymers from plants, offer unique properties for creating advanced conjugates. These mannan conjugates show great potential in tissue engineering, diagnostics, and therapeutics.

Area of Science:

  • Polymer Chemistry
  • Biomaterials Science

Background:

  • Mannans are key structural polysaccharides in gymnosperm wood and non-leguminous plant seeds.
  • They possess valuable physico-chemical properties like viscosity, solubility, and gelling ability, alongside biocompatibility, biodegradability, and non-toxicity.

Purpose of the Study:

  • To review synthesis strategies for mannans.
  • To explore various fabrication methods for mannan conjugates.
  • To highlight the diverse applications of mannan conjugates.

Main Methods:

  • The review covers synthesis strategies for mannans.
  • Fabrication methods discussed include reductive amination, aminoxyligation, carbodiimide coupling, mannosylation, and cyanylation.
  • Applications are explored across multiple scientific domains.
Keywords:
4-mannanMannansadjuvantsallergen tolerancegene therapyimmune responsenanoparticlesvaccine deliveryβ-1

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Related Experiment Videos

Last Updated: May 11, 2026

Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines
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Published on: November 25, 2017

Exploring Protein-Glycan Interactions: Advances in Nuclear Magnetic Resonance
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Engineering Antiviral Agents via Surface Plasmon Resonance
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Main Results:

  • Mannans can be effectively conjugated with drugs, carriers, and biomolecules to enhance their efficacy.
  • Conjugation strategies leverage various chemical coupling techniques.
  • Mannan conjugates demonstrate broad utility in advanced applications.

Conclusions:

  • Mannan conjugates are versatile biomaterials with significant potential.
  • Their applications span tissue engineering, diagnostics, vaccine delivery, therapeutics, and biomedicine.
  • Further research into mannan conjugation promises innovative biomedical solutions.