TGL / HDL - C ratio and non-HDL-C - prognostic index in chronic kidney disease

Dyslipidemia, a major risk factor for chronic kidney disease (CKD) affects more than ten percent of the general population. Dyslipidemia in CKD, if left untreated, will result in end stage renal disease. So, the relationship between atherogenic lipid profile ratios and the assessment of CKD severity is a potential area still to be explored. In assessing the severity of CKD, these ratios have higher prognostic value than individual parameters alone. Therefore, it is of interest to evaluate the role of TGL/HDL- c ratio and NON- HDL-c levels in assessing the disease severity in CKD. Cross-sectional study with one hundred and thirteen CKD patients divided into two groups based-on e-GFR levels and CKD-EPIDEMIOLOGY Staging. Quantitative measurements of lipid profile parameters (total cholesterol, triglycerides, HDL-c) done by enzymatic colorimetric method and renal function test by spectrophotometric method. TGL: HDL-c and NON- HDL-c levels were calculated, Statistical data analyzed using SPSS version software 16.0 showed TGL / HDL- c ratio and NON-HDL-c values has significant correlation with CKD staging and found to highly significant (p <0.001). TGL / HDL-c ratio and NON-HDL-c value can be used as a prognostic index in CKD patients.