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Updated: May 12, 2026

Breeding by Design for Functional Rice with Genome Editing Technologies
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Genome Editing in Root and Tuber Crop Development in Sub-Saharan Africa.

Himanshu Saini1,2, Rohit Kumar3, Manjeet4

  • 1School of Applied Natural Science Adama Science and Technology University Adama Ethiopia.

Plant-Environment Interactions (Hoboken, N.J.)
|May 11, 2026
PubMed
Summary

Genome editing advances crop improvement for vital root and tuber crops. This review covers CRISPR/Cas9 applications, challenges like plant regeneration, and solutions for resilient food systems.

Keywords:
CRISPR/Cas9climate change resiliencecrop improvementprecision genome editingroot and tuber crops

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Area of Science:

  • Agricultural Science
  • Biotechnology
  • Genetics

Background:

  • Root and tuber crops (potato, cassava, sweet potato, yam) are crucial for global food security.
  • These crops face significant threats from climate change, pests, diseases, and limited genetic diversity.
  • Genome editing offers a powerful tool to enhance desirable traits in these essential crops.

Purpose of the Study:

  • To synthesize recent advances in genome editing for root and tuber crops.
  • To examine technical and regulatory challenges hindering genome editing adoption.
  • To propose next-generation strategies for complex trait engineering in these crops.

Main Methods:

  • Review of current literature on genome editing in root and tuber crops.
  • Analysis of global production systems and specific initiatives, including in Sub-Saharan Africa.
  • Examination of technical constraints (transformation, regeneration) and regulatory landscapes.

Main Results:

  • Genome editing enables targeted improvements like disease resistance, stress tolerance, nutritional quality, and shelf life.
  • Key challenges include low transformation/regeneration efficiency and diverse international regulatory policies.
  • Emerging solutions like genotype-independent and DNA-free editing are discussed.

Conclusions:

  • Genome editing is vital for developing resilient and sustainable food systems through improved root and tuber crops.
  • Addressing technical and regulatory hurdles is critical for widespread adoption.
  • Next-generation strategies are needed for engineering complex traits, especially in polyploid species.