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Advanced Gastric Cancer Presenting as a Giant Subepithelial Lesion: A Case Report

Ji Sun1, Qian Wang2, Yuemei Hu3

  • 1Department of Gastroenterology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine Shanghai China.

Clinical Case Reports
|May 11, 2026
PubMed

Keywords:
Helicobacter pyloridiagnosisgastric cancersubepithelial lesion

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Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...