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Updated: May 12, 2026

Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
Management of Mixed Mechanism Glaucoma Secondary to NewColorIris Implant Using an Ab Externo Xen Gel Stent
Roshun Sangani1, Param Shukla1, Miriam M Habiel1
1Institute of Ophthalmology & Visual Science, Rutgers New Jersey Medical School, Newark, New Jersey, USA, rutgers.edu.
Background And Aims:
We present a case of mixed mechanism glaucoma following NewColorIris implant that was successfully treated using an off-label use of Xen Gel Stent.
Methods:
A retrospective review of the patient's medical records was conducted following the acquisition of informed consent.
Results:
A 42-year-old female with a history of bilateral cosmetic iris implants presented to the emergency room due to corneal decompensation and a secondary mixed mechanism glaucoma caused by implant iris chafing in her left eye. The patient underwent prosthetic iris implant removal and had persistently elevated intraocular pressures (IOPs) postoperatively. She underwent a subsequent off-label Xen Gel Stent implantation which has successfully controlled her eye pressures without the need for supplementary antiglaucoma medications for 13 months. This off-label use of the Xen Gel Stent helped the patient maintain excellent IOP and satisfied the patient's cosmetic preferences.
Conclusion:
Xen Gel Stent may be a safe and effective option to treat secondary glaucoma due to cosmetic iris implants.
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