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Updated: May 12, 2026

Voltage-Dependent Potassium Current Recording on H9c2 Cardiomyocytes via the Whole-Cell Patch-Clamp Technique
08:11

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Published on: November 11, 2022

Importance of History in the Management of New-Onset Hyperkalemia

Igor Kagan1, Kristine Sarmosyan1, Sean Lei1

  • 1Division of Nephrology, University of California Los Angeles David Geffen School of Medicine, Los Angeles, USA.

Cureus
|May 11, 2026
PubMed

Hyperkalemia is a life-threatening disorder with a multitude of causes. We present a case of a 64-year-old woman with new-onset hyperkalemia. A patient with a documented history of normokalemia developed consistent hyperkalemia on repeat blood testing. The patient was initially managed by her primary care physician, then referred to nephrology for persistent hyperkalemia, at which point sodium polystyrene sulfonate was initiated. The patient presented for a second opinion on the hyperkalemia, and after a thorough history and chart review, it was determined that the patient's dorzolamide-timolol eye drops were the cause of the hyperkalemia. Discontinuation of the eye drops resolved the hyperkalemia.

Keywords:
drug-induced hyperkalemiaelectrolyte abnormalitiesgeneral nephrologyhyperkalemia managementtimolol eye drops

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