Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Controversies in Treatment Methodologies in Cerebrovascular Surgery.

Advances and technical standards in neurosurgery·2026

Same author

Normalized air/brain volume ratio (Air-Brain Index) as a postoperative marker of delayed chronic subdural hematoma after clipping of unruptured cerebral aneurysms.

Neurosurgical review·2026

Same author

How I do it: Endoscopic microvascular decompression with vertebral artery transposition for trigeminal neuralgia caused by vertebrobasilar dolichoectasia.

Acta neurochirurgica·2026

Same author

Ten-Year Trends in First- and Second-Line <i>Helicobacter pylori</i> Eradication Rates at a Regional Hospital in Japan.

Juntendo medical journal·2026

Same author

Comparative evaluation of total intravenous anaesthesia versus inhalational anaesthesia on postoperative recovery in elective abdominal surgery.

Bioinformation·2026

Same author

Bispectral index-guided versus standard anaesthesia monitoring for intraoperative awareness prevention.

Bioinformation·2026

Search research articles

Related Experiment Video

Updated: May 12, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

Predicting Atherosclerosis in Unruptured MCA Aneurysm with Computational Fluid Dynamics Study.

Brajesh Kumar¹, Niraj Kanaujia¹, Zeenat S Imam²

¹Department of Neurosurgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.

Asian Journal of Neurosurgery

|May 11, 2026

Summary

Computational fluid dynamics (CFD) can predict atherosclerotic changes in middle cerebral artery (MCA) aneurysms by analyzing wall pressure and shear stress. This study correlated CFD findings with intraoperative observations, suggesting CFD

Keywords:

CFD MCA aneurysm atherosclerosis

More Related Videos

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery

Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery

Published on: December 6, 2024

Related Experiment Videos

Last Updated: May 12, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery

Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery

Published on: December 6, 2024

Area of Science:

Medical Imaging
Computational Fluid Dynamics
Vascular Surgery

Background:

Atherosclerotic changes in middle cerebral artery (MCA) aneurysms pose risks of emboli and distal arterial occlusion.
Computational fluid dynamics (CFD) is being explored as a diagnostic tool for aneurysm hemodynamics.
Predicting atherosclerotic changes in MCA bifurcation aneurysms is crucial for surgical planning.

Purpose of the Study:

To evaluate CFD as a tool for predicting atherosclerotic changes in unruptured MCA bifurcation aneurysms.
To correlate CFD findings with intraoperative microscopic observations of MCA aneurysms.
To investigate the relationship between CFD-derived hemodynamic parameters and atherosclerosis in MCA aneurysms.

Main Methods:

Retrospective review of intraoperative video recordings of MCA bifurcation aneurysms (September 2014 - May 2017).
Analysis of MCA bifurcation aneurysms with atherosclerotic changes using CFD, examining wall pressure, wall shear stress (magnitude and vectors), and flow patterns.
Correlation of CFD findings with intraoperative observations in patients who underwent open surgery.

Main Results:

Decreased wall pressure observed in atherosclerotic segments of MCA aneurysms.
Low shear stress magnitude and divergent shear stress vectors identified in atherosclerotic segments.
Four cases demonstrated moderately decreased wall pressure and decreased wall shear stress magnitude in atherosclerotic areas.

Conclusions:

CFD shows potential in identifying hemodynamic changes associated with atherosclerosis in MCA aneurysms.
Findings suggest a correlation between decreased wall pressure and low shear stress with atherosclerotic changes.
Larger, multicentric studies are needed to establish statistical significance and validate CFD's predictive capabilities for MCA aneurysm atherosclerosis.