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Peripheral refractive errors in pseudophakic eyes: in vitro evaluation and optical simulation.
D Romashchenko1, A Del Aguila1, M State1
1Johnson & Johnson MedTech, Van Swietenlaan 5, 9728NX, Groningen, The Netherlands.
Biomedical Optics Express
|May 11, 2026
Summary
Peripheral refractive errors in pseudophakic eyes were assessed. All intraocular lens (IOL) models showed similar peripheral cylinder, indicating consistent optical performance across different IOL types and technologies.
Area of Science:
- Ophthalmology
- Optical Engineering
- Biomedical Optics
Background:
- Pseudophakic eyes, those with an implanted intraocular lens (IOL), can experience peripheral refractive errors.
- Understanding these errors is crucial for optimizing visual quality after cataract surgery.
Purpose of the Study:
- To systematically assess peripheral refractive errors, specifically peripheral cylinder, in pseudophakic eyes.
- To compare the peripheral optical performance of various intraocular lens (IOL) types and technologies.
Main Methods:
- Optical bench measurements using a physical eye model with eight different IOL models (20 D approximate power).
- Inclusion of various IOL types (monofocal, EDOF, multifocal) and technologies (refractive, diffractive, wavefront-shaping).
- Optical simulations performed on average and personalized pseudophakic eye models.
Main Results:
- Peripheral cylinder at a 20° visual field was consistent across all tested IOLs, ranging from -2.24 to -2.87 D.
- Simulations indicated peripheral cylinder was largely independent of pupil size, retinal radius of curvature (ROC), and IOL technology in average eye models.
- Peripheral blur showed minor variations with IOL technology and ROC but was minimally affected by pupil size.
Conclusions:
- The peripheral optical performance, particularly peripheral cylinder, is comparable across a wide range of modern intraocular lens (IOL) technologies.
- IOL technology and eye-specific parameters have a limited impact on peripheral cylinder and blur in pseudophakic eyes.

