Related Experiment Video
Updated: May 12, 2026

A Novel Approach to Overcome Movement Artifact When Using a Laser Speckle Contrast Imaging System for Alternating Speeds of Blood Microcirculation
Published on: August 30, 2017
Green channel-informed collaborative filtering for high-fidelity laser speckle contrast imaging in dual-display
Yadi Xue1,2, Jialin Liu1,3,4,5, Wei Zhou1,2
1Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, 88 Keling Road, Suzhou, Jiangsu 215163, China.
None:
The dual-display laparoscopic imaging system (DLIS), which integrates laser speckle contrast imaging (LSCI) with white-light RGB mode, enhances surgical decision-making during minimally invasive procedures. However, motion artifacts and dynamic perfusion necessitate reduced statistical frames, which increases noise and degrades imaging quality. Although the structure-guided anisotropic approach optimizes local contrast calculation, it fails to suppress global statistical noise. To address this, we propose a green (G) channel-informed collaborative filtering framework, which leverages the hemoglobin-absorption-induced intensity variations in the green channel as a robust physical prior to locate non-local similar patches and perform principal component analysis (PCA)-based collaborative denoising. This approach achieves high-fidelity microvascular perfusion reconstruction in both few-frame temporal and single-image spatial LSCI. The proposed method suppresses the statistical noise and restores the high-fidelity perfusion map, which preserves the dynamic perfusion of microvessels.
