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Published on: January 5, 2024
Knowledge, attitudes, and practices of patients with multiple myeloma regarding venous thromboembolism: a
Rui Zhang1, Yue Weng1, Shuting Wu1
1Hematological Department, Bazhong Central Hospital, Bazhong, Sichuan, China.
Introduction:
Venous thromboembolism (VTE) is a significant complication in multiple myeloma (MM) patients, yet patient awareness and preventive behaviors in this population have received limited research attention.
Methods:
This cross-sectional survey, conducted at Bazhong Central Hospital (January-September 2024), assessed the knowledge, attitudes, and practices (KAP) of 504 MM patients regarding VTE.
Results:
Participants were predominantly male (65.1%), with 57.7% reporting prior VTE. Mean scores (SD) were suboptimal: knowledge (8.97 ± 2.92, range 0-13), attitude (29.59 ± 2.70, range 14-70), and practice (44.03 ± 4.07, range 10-50). Positive correlations were found between knowledge-attitude (r = 0.141, P = 0.002), knowledge-practice (r = 0.281, P < 0.001), and attitude-practice (r = 0.159, P < 0.001). Structural equation modeling revealed knowledge directly influenced attitude (β = 0.761, P < 0.001), attitude directly affected practice (β = 0.806, P < 0.001), and knowledge indirectly impacted practice via attitude (β = 0.613, P < 0.001).
Discussion:
Findings highlight gaps in VTE knowledge and negative attitudes among MM patients, despite proactive practices. Improving patient education on VTE may enhance attitudes and behaviors, potentially reducing VTE risk in this high-risk population. Targeted interventions are warranted to optimize VTE prevention strategies.
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