Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 12, 2026

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
03:14

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness

Published on: December 6, 2024

Personalized Case- and Evidence-Based TBI Prognosis with Small Language Models.

Pranav Manjunath1, Syed M Adil2, Benjamin D Wissel2

  • 1Dept. of Biomedical Engineering, Duke University, Durham, USA.

... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics
|May 11, 2026
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Towards Interactive and Interpretable Image Retrieval-Based Diagnosis: Enhancing Brain Tumor Classification with LLM Explanations and Latent Structure Preservation.

Artificial intelligence in medicine. Conference on Artificial Intelligence in Medicine (2005- )·2026
Same author

The role of the blink reflex in predicting facial nerve outcomes following vestibular schwannoma surgery: a 4-year retrospective review.

Journal of neurosurgery·2026
Same author

Long-term stability of language with remapping in patients with medically refractory epilepsy.

Journal of neurosurgery·2026
Same author

The effect of sex on vestibular schwannoma incidence varies across the lifespan and modifies associations with race/ethnicity.

Journal of neuro-oncology·2026
Same author

Co-delivery of synaptogenic and angiogenic nanoparticles in MAP scaffolds enhances post-stroke synapse formation.

Journal of materials chemistry. B·2026
Same author

Delivery of Angiogenic Therapy from Flowable Hyaluronic Acid Porous Scaffolds Results in Functional Improvement without Anti-Inflammatory Agents.

Advanced functional materials·2026
Same journal

Dual-Attention BiLSTM for Interpretable Forecasting of Treatment Toxicities.

... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics·2026
Same journal

Integrating Neuroimaging and Genetics via Contrastive Learning for Working Memory.

... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics·2026
Same journal

Interrelation Among the Developmental Trajectories of Brain, Cognition and Behavior During Adolescence.

... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics·2026
Same journal

Bidirectional Translation Between ECG and PCG.

... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics·2026
Same journal

Caudal and Thalamic Segregation in White Matter Brain Network Communities in Alzheimer's Disease Population.

... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics·2025
Same journal

RBAD: A Dataset and Benchmark for Retinal Vessels Branching Angle Detection.

... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics·2025
See all related articles

This study introduces a dual retrieval AI framework for traumatic brain injury (TBI) patient disposition, combining small language models with clinical guidelines and similar patient cases for improved accuracy and personalized decision-making.

Area of Science:

  • Artificial Intelligence in Medicine
  • Clinical Decision Support Systems
  • Traumatic Brain Injury Management

Background:

  • Emergency department disposition for traumatic brain injury (TBI) relies on complex data synthesis, often using heuristics leading to variable outcomes.
  • Large language models (LLMs) offer potential for evidence-based practice but face limitations in size, cost, and privacy for clinical use.

Purpose of the Study:

  • To develop a dual retrieval-augmented framework using efficient, on-premise small language models (SLMs) for personalized TBI patient disposition.
  • To integrate evidence-based practice (guideline retrieval) with case-based reasoning (similar patient exemplars) for enhanced prediction.

Main Methods:

  • Implemented a dual retrieval framework with two open-source SLMs (Phi-4-mini, Qwen-2.5) under 4B parameters.
Keywords:
Case-based ReasoningED DispositionEvidence-based PracticeSmall Language ModelsTraumatic Brain Injury

Related Experiment Videos

Last Updated: May 12, 2026

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
03:14

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness

Published on: December 6, 2024

  • Modeled evidence-based practice by retrieving patient-specific guideline passages.
  • Utilized case-based reasoning to retrieve similar patients as few-shot exemplars for personalized context.
  • Main Results:

    • Similar patient exemplars consistently improved classification performance (sensitivity without sacrificing specificity) across both SLMs.
    • Clinical guidelines had a smaller impact individually but shifted predictions towards guideline-consistent behavior when combined with exemplars.
    • Clinician evaluations indicated that exemplars enhance accuracy, while guidelines improve clinical relevance and justification of AI outputs.

    Conclusions:

    • Targeted retrieval personalizes AI predictions and their rationale, improving performance, interpretability, and trustworthiness in clinical decision-making.
    • The dual retrieval framework offers a viable approach for deploying AI in TBI disposition, balancing accuracy with clinical relevance.