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Updated: May 12, 2026
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Screening for Phytoestrogens using a Cell-based Estrogen Receptor β Reporter Assay
Published on: June 7, 2020
No distinct estrogenic or androgenic activity was observed in Korean Red Ginseng metabolites prepared using a S9
NamKyu Lee1, YiSi Yang1, DeYu Tian1
1Department of Integrative Bioscience and Biotechnology, College of Life Science, Sejong University, Seoul, 05006, Republic of Korea.
Journal of Ginseng Research
|May 11, 2026
Abstract:
We determined whether Korean Red Ginseng (KRG) extract and ginsenosides (Rb1, Rg1, or Rg3) have estrogen receptor-mediated or androgen receptor-mediated activities using OECD TG455/458 assays with S9 metabolic activation. They did not elicit both hormonal receptor-mediated responses. KRG extract and ginsenosides do not have male and female sex hormone-like activity.
