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Development of an excel-based decision support tool for graves orbitopathy
1Department of Ophthalmology, Worldeye Hospital, Izmir, Türkiye.
Orbit (Amsterdam, Netherlands)
|May 11, 2026
Summary
A new Excel tool operationalizes European Group on Graves
Area of Science:
- Ophthalmology
- Endocrinology
- Clinical Decision Support Systems
Background:
- Graves' orbitopathy (GO) management requires adherence to complex guidelines.
- Operationalizing the 2021 European Group on Graves' Orbitopathy (EUGOGO) recommendations in clinical practice presents challenges.
- Standardizing GO care is crucial for consistent patient outcomes.
Purpose of the Study:
- To develop and assess the technical feasibility of a rule-based Excel decision support tool.
- To operationalize the 2021 EUGOGO recommendations for Graves' orbitopathy (GO).
- To facilitate the integration of GO management guidelines into routine clinical practice.
Main Methods:
- A rule-based Excel tool was developed integrating EUGOGO inputs (CAS, severity, GO-QoL).
- Progression parameters served as override criteria for disease activity classification.
- Proof-of-concept validation used clinical case scenarios against expert decisions.
Main Results:
- The tool produced structured summaries of disease activity, severity, and management options.
- Automated outputs were generated from routinely collected clinical parameters.
- Pilot use confirmed technical feasibility and internal consistency of rule execution.
Conclusions:
- A pragmatic, rule-based Excel tool can operationalize EUGOGO recommendations for GO.
- The tool supports documentation and workflow in GO management.
- Further validation and prospective evaluation are necessary.
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