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Updated: May 12, 2026

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
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Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

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Preoperative Corticosteroid Injection and Postoperative Infection Following De Quervain's Release: A National

Mikayla P Borusiewicz1, Thompson Zhuang1, David R Steinberg1

  • 1Hospital of the University of Pennsylvania, Philadelphia, USA.

Hand (New York, N.Y.)
|May 11, 2026
PubMed
Summary

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Corticosteroid injections before De Quervain's release surgery do not increase surgical site infection risk. This finding applies to injections given within 90 days, and even 60 days, prior to the procedure.

Area of Science:

  • Orthopedic Surgery
  • Musculoskeletal Disorders
  • Pharmacology

Background:

  • De Quervain's tenosynovitis is commonly treated with conservative measures including corticosteroid injections.
  • Surgery may be necessary for refractory cases, but the impact of prior injections on surgical outcomes is unknown.
  • This study investigates the potential link between corticosteroid injections and adverse outcomes following surgical release for De Quervain's tenosynovitis.

Purpose of the Study:

  • To determine if corticosteroid injections administered within 3 months before De Quervain's release surgery increase the risk of postoperative surgical site infection.
  • To assess the association between recent corticosteroid injections and other adverse surgical outcomes like reoperation or wound dehiscence.

Main Methods:

  • A national administrative database was used to identify adult patients who underwent De Quervain's release.
Keywords:
De Quervain’s tenosynovitisanatomycorticosteroiddiagnosisglucocorticoidinfectioninjectionoutcomesresearch & health outcomeswrist

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Last Updated: May 12, 2026

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
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  • Patients were categorized into two groups: those who received a corticosteroid injection within 90 days prior to surgery and those who did not.
  • Propensity score matching was employed to control for confounding variables, followed by assessment of surgical site infection, reoperation, and wound dehiscence rates.
  • Main Results:

    • No statistically significant increase in surgical site infections was observed in patients who received a corticosteroid injection within 90 days prior to surgery.
    • Rates of return to the operating room for infection and wound dehiscence were similar between the groups.
    • A sensitivity analysis confirmed no increased risk of surgical site infection when injections were given within 60 days before surgery.

    Conclusions:

    • Corticosteroid injections administered within 90 days prior to De Quervain's release surgery are not associated with an elevated risk of postoperative surgical site infection.
    • The findings extend to a 60-day window, indicating that recent corticosteroid injections do not compromise surgical site integrity or increase infection risk.
    • This suggests that corticosteroid injections can be safely administered prior to surgical intervention for De Quervain's tenosynovitis without compromising surgical outcomes.