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Allergic Diseases and Head and Neck Cancer: A Systematic Review and Meta-analysis
Daniel Karlsson1, Amanj Saber2
1School of Medical Science, Faculty of Medicine and Health, Örebro University, Örebro, Sweden. daniel.karlsson92@gmail.com.
Iranian Journal of Allergy, Asthma, and Immunology
|May 11, 2026
Summary
This meta-analysis found no overall link between allergic diseases and head and neck cancer. However, specific allergies like asthma and food allergies showed protective effects, while allergic rhinitis had mixed associations depending on cancer site.
Area of Science:
- Epidemiology
- Oncology
- Immunology
Background:
- Allergic disorders are prevalent globally.
- The association between allergies and head and neck cancer (HNC) is inconsistent.
- Understanding this relationship is crucial for public health.
Conclusions:
- The relationship between allergies and HNC is complex and multifaceted.
- Specific allergic conditions exhibit differential associations with various HNC subsites.
- Further research is warranted to elucidate these intricate associations and their underlying mechanisms.
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