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Pediatric Allergic Contact Dermatitis: Sensitization Patterns for a Practical Panel

Merve Şendal1, Nilay Çalışkan2, Deniz Ozceker3

  • 1Department of Pediatrics, Prof. Dr. Cemil Taşçıoğlu City Hospital, Saglik Bilimleri University, Istanbul, Turkey.

International Archives of Allergy and Immunology
|May 11, 2026
PubMed

Insights

A shortened patch test panel, including 14 key allergens, effectively diagnoses allergic contact dermatitis (ACD) in children. This approach addresses challenges in pediatric allergy testing and improves diagnostic feasibility for young patients.

Area of Science:

  • Dermatology
  • Pediatric Allergy
  • Diagnostic Immunology

Background:

  • Allergic contact dermatitis (ACD) is a growing concern in children.
  • Standard patch testing faces challenges in pediatric populations due to panel limitations and practical constraints.
  • Developing evidence-based pediatric-specific patch test panels is crucial for accurate diagnosis.

Purpose of the Study:

  • To evaluate a practical and shortened patch test panel for diagnosing ACD in children.
  • To identify the most relevant allergens for pediatric patients.
  • To improve the feasibility of patch testing in pediatric settings.

Main Methods:

  • Retrospective analysis of pediatric patients diagnosed with ACD between 2017 and 2021.
  • Patch testing performed using the Thin-Layer Rapid-Use Epicutaneous (T.R.U.E.) Test.
  • Allergen positivity evaluated across different age groups.

Main Results:

  • Nickel was the most common allergen identified in children.
  • Formaldehyde resin, isothiazolinones, and fragrance mix were frequent sensitizers in younger children.
  • A 14-allergen panel successfully identified relevant sensitizations in all pediatric age groups.

Conclusions:

  • Shortened, targeted patch test panels enhance diagnostic feasibility for pediatric ACD.
  • This approach is particularly beneficial in resource-limited settings or when extensive allergen series are unavailable.
  • Optimized patch testing improves the management of allergic contact dermatitis in children.
Abstract

Keywords:
Atopy patch testChildrenContact dermatitis

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