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Prehabilitation in Solid Organ Transplant Candidates: A Systematic Review and Meta-analysis
Yuxiao Chen1,2, Raquel Sebio-Garcia1,3, Edgar Iglesias-Garcia1,4
1Physical Medicine and Rehabilitation Department, Hospital Clínic de Barcelona, Barcelona, Spain.
Transplantation
|May 11, 2026
Summary
Prehabilitation may shorten hospital stays and improve walking distance for solid organ transplant candidates. However, evidence quality is low to moderate, with concerns about program effectiveness in some studies.
Area of Science:
- Transplant Medicine
- Rehabilitation Science
- Clinical Outcomes Research
Background:
- Solid organ transplant (SOT) candidates frequently experience functional decline during waiting periods.
- Prehabilitation has demonstrated benefits in other high-risk surgical settings, but data for SOT is limited.
Conclusions:
- Prehabilitation shows potential to reduce hospital length of stay and enhance functional capacity in SOT candidates.
- Despite promising trends, the low to moderate certainty of evidence and identified risks of ineffectiveness necessitate cautious interpretation and further high-quality research.
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