Related Experiment Video
Updated: May 13, 2026
Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
Published on: September 16, 2025
The Comparison of Contrast Sensitivity After Keratorefractive Lenticule Extraction Between the VisuMax 800 and 500
Jiayi Hu1,2,3,4,5, Zhanying Wang1,2,3,4,5, Yongle Bao1,2,3,4,5,6
1Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University.
Purpose:
To compare the contrast sensitivity (CS) after keratorefractive lenticule extraction (KLEx) between the VisuMax 800 and VisuMax 500 systems (Carl Zeiss Meditec AG).
Methods:
Participants aged 18 to 46 years were recruited between November 2024 and April 2025. Visual and refractive outcomes were assessed and CS function (CSF) was measured using the quantitative CSF (qCSF) test at 1, 3, and 6 months postoperatively. The differential analysis and influencing factor analysis of qCSF parameters between the two systems were conducted.
Results:
In the VisuMax 800 group, qCSF parameters at 1 month postoperatively were better than those in the VisuMax 500 group (P < .05). There were no statistically significant differences in qCSF parameters between the two groups at 3 and 6 months postoperatively (P > .05). In the VisuMax 500 group, preoperative and postoperative cylindrical refraction were significantly correlated with CS (6 cycles per degree [cpd]) and CS (12 cpd) (P < .05). In the VisuMax 800 group, preoperative and postoperative spherical refraction (SR) and postoperative SR was were significantly correlated with CS (6 cpd) and CS (12 cpd) (P < .05). CS (12 cpd) in the VisuMax 500 group and CS (6 cpd) in the VisuMax 800 group were correlated with the optical zone (P < .05).
Conclusions:
The VisuMax 800 system demonstrates a slight advantage in the early recovery of visual function following KLEx, particularly excelling in CS at medium and high spatial frequencies, and its outcomes converge with those of the VisuMax 500 system at postoperative 3 and 6 months.