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Related Concept Videos

Infertility in Females01:28

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of endometrial...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

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Response to "Comment on Cancer Treatment Modalities and Female Fertility Preservation".

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Related Experiment Video

Updated: May 13, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
08:46

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

Cancer Treatment Modalities and Female Fertility Preservation.

Seonga Song1, Lilia Davenport2, Samantha Paone3

  • 1Hematology and Oncology, NYU Langone Hospital-Long Island, Mineola, New York, USA.

Pharmacotherapy
|May 11, 2026
PubMed
Summary

Oncofertility integrates oncology and reproductive endocrinology to address cancer treatment

Keywords:
chemotherapycryopreservationfertilityfertility preservationpharmacistssurvivorshipwoman's health

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Last Updated: May 13, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
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Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

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Collection of Human Follicular Fluid, Follicle Somatic Cells, and Immature Oocytes from Individuals Undergoing In Vitro Fertilization
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Fertility Preservation in Patients with Severe Ovarian Dysfunction
12:03

Fertility Preservation in Patients with Severe Ovarian Dysfunction

Published on: March 25, 2021

Area of Science:

  • Reproductive Endocrinology
  • Oncology
  • Pharmacology

Background:

  • Cancer treatments, including radiation and novel therapies like targeted monoclonal antibodies and kinase inhibitors, can significantly impact female fertility.
  • The scope of cancer treatments has expanded, necessitating a comprehensive understanding of their diverse effects on reproductive health.

Purpose of the Study:

  • To review the current literature on the effects of various cancer treatment modalities on female fertility.
  • To summarize available fertility preservation options for female cancer patients.
  • To outline the role of pharmacists within the oncofertility practice.

Main Methods:

  • Comprehensive literature review of studies on cancer treatments and female fertility.
  • Analysis of current fertility preservation techniques and their efficacy.
  • Examination of the multidisciplinary approach in oncofertility, including the pharmacist's contribution.

Main Results:

  • Cancer therapies, beyond traditional DNA-damaging agents, present varied risks to female fertility.
  • A range of fertility preservation options are available for female patients undergoing cancer treatment.
  • Pharmacists play a crucial role in patient counseling and management within oncofertility.

Conclusions:

  • Oncofertility care is essential for patients undergoing cancer treatment to mitigate infertility risks.
  • Multidisciplinary collaboration is key to optimizing fertility preservation outcomes.
  • Further research is needed to fully understand the long-term reproductive effects of newer cancer therapies.