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Updated: May 13, 2026
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A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
Trends in Gestational Diabetes Identified through Universal Screening: A Population-Based Observational Study
István Panykó1,2,3, Attila Kun4, Gergely Á Visolyi1,3,5
1Department of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.
Summary
Gestational diabetes (GDM) prevalence and glucose levels increased in Hungary from 2010-2017. Rising BMI during pregnancy, particularly between trimesters, significantly contributed to this GDM epidemic.
Area of Science:
- Obstetrics and Gynecology
- Endocrinology
- Public Health
Background:
- Gestational diabetes mellitus (GDM) is a growing global health concern.
- Understanding temporal trends and contributing factors is crucial for effective public health strategies.
Purpose of the Study:
- To investigate trends in GDM prevalence and glucose levels in Hungary (2010-2017).
- To identify determinants, specifically Body Mass Index (BMI), associated with GDM trends.
Main Methods:
- Cross-sectional study utilizing universal GDM screening (3-point 75g OGTT) in Tolna County, Hungary.
- Analysis of singleton pregnancies (n=7071) between 2010-2017, including early pregnancy and OGTT BMI data.
- Multiple logistic and linear regression models were used to assess trends and determinants.
Main Results:
- GDM prevalence rose from 15% to 20% (5% increase) between 2010-2017.
- Fasting, 1-hour, and 2-hour post-load glucose levels significantly increased.
- Increasing BMI at OGTT explained 25-30% of the rise in GDM diagnosis and fasting glucose.
Conclusions:
- BMI gain during the first two trimesters is a key driver of the GDM epidemic in Hungary.
- Targeting both early-pregnancy BMI and BMI gain during gestation is essential for GDM prevention.
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