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Related Experiment Video

Updated: May 13, 2026

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
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Landscape and trends in postoperative cognitive dysfunction: A bibliometric and visualized analysis.

Wei Gan1, Qiaoning Li, Jinchun Xie

  • 1Department of General Surgery, General Hospital of Western Theater Command, Chengdu Sichuan, P.R.China.

Medicine
|May 12, 2026
PubMed
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Global research on postoperative cognitive dysfunction (POCD) is rapidly expanding. Future studies should investigate POCD etiology and mechanisms, with perioperative neurocognitive disorder remaining a key research area.

Area of Science:

  • Anesthesiology
  • Neuroscience
  • Bibliometrics

Background:

  • Postoperative cognitive dysfunction (POCD) is a complex and extensively researched topic in anesthesiology.
  • Despite significant research, the pathogenesis of POCD remains unclear, and global research trends require analysis.

Purpose of the Study:

  • To conduct a bibliometric analysis of research on POCD over the past 30 years.
  • To identify global research trends, key institutions, influential publications, and emerging hotspots in POCD research.

Main Methods:

  • Bibliometric analysis of 2290 articles published between January 1, 1993, and December 31, 2022.
  • Data sourced from Web of Science, with visualization and analysis performed using CiteSpace and VOSviewer.

Main Results:

Keywords:
bibliometricsneuropsychological testsperioperative neurocognitive disorderpostoperative cognitive complicationspostoperative cognitive dysfunctionsurgeryvisual analysis

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  • China leads in publication volume, while the United States shows higher research centrality.
  • Capital Medical University and Duke University are leading institutions in POCD research.
  • Key research hotspots include neuroinflammation, cardiac surgery, delirium, general anesthesia, and perioperative neurocognitive disorder.

Conclusions:

  • Global research on POCD is experiencing rapid growth.
  • Future research should prioritize understanding the etiology and mechanisms of POCD.
  • Perioperative neurocognitive disorder is identified as a significant and ongoing frontier in POCD research.