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Safety and efficacy of ERCP using standard duodenoscopes in pediatric patients with choledocholithiasis: A
Berk Baş1, Ömer Küçükdemirci2,3, Müge Ustaoğlu3
1Department of Gastroenterology and Hepatology, Adnan Menderes University, School of Medicine, Aydin, Türkiye.
Insights
Endoscopic retrograde cholangiopancreatography (ERCP) is safe and effective for pediatric choledocholithiasis. Success rates and complications in children are comparable to adults, supporting its use in pediatric patients.
Area of Science:
- Gastroenterology
- Pediatric Endoscopy
- Biliary Tract Interventions
Background:
- Choledocholithiasis in children presents unique challenges, particularly regarding the use of standard adult duodenoscopes.
- Evaluating the safety and efficacy of ERCP in pediatric patients is crucial for establishing best practices.
Purpose of the Study:
- To assess the safety and efficacy of endoscopic retrograde cholangiopancreatography (ERCP) in pediatric patients with choledocholithiasis.
- To compare ERCP outcomes in children versus adults using standard adult duodenoscopes.
Main Methods:
- Retrospective review of 70 pediatric patients (ages 2-13) who underwent ERCP for choledocholithiasis.
- Comparison with a control group of 397 adult patients with similar conditions.
- Analysis of procedural success (deep cannulation, stone extraction) and complication rates.
Main Results:
- Procedural success rate in the pediatric group was 91.4%, comparable to 95.2% in adults (P=.278).
- Low complication rates in children: bleeding (8.6%), pancreatitis (1.4%).
- No mortalities reported in the pediatric cohort.
Conclusions:
- ERCP using standard adult duodenoscopes is safe and effective for pediatric choledocholithiasis when performed by experienced endoscopists.
- Pediatric ERCP outcomes are comparable to adult outcomes.
- Further multicenter studies and enhanced pediatric training are recommended to optimize outcomes.
Abstract:
This study aimed to evaluate the safety and efficacy of endoscopic retrograde cholangiopancreatography (ERCP) in children aged 2 to 13 years with choledocholithiasis, addressing the challenges of using standard adult duodenoscopes in a pediatric population. Materials and Methods: We retrospectively reviewed the medical records of 107 patients who underwent ERCP at a single tertiary ERCP center between 2014 and 2024. Among these, patients with chronic pancreatitis or biliary strictures were excluded, resulting in a final cohort of 70 pediatric patients. A control group of 397 adult patients with similar conditions was analyzed for comparison. Procedural success was defined as successful deep cannulation of the common bile duct and stone extraction. The pediatric group achieved a procedural success rate of 91.4%, compared to 95.2% in adults, with no statistically significant difference (P = .278). Complication rates were low and similar between groups: bleeding occurred in 8.6% of pediatric patients, while pancreatitis was noted in 1.4%. No mortalities were reported in the pediatric cohort. The findings indicate that ERCP can be performed safely and effectively in children using standard adult duodenoscopes by experienced adult gastroenterologists under proper supervision. The procedural success rates and complication rates were comparable to adults, suggesting that ERCP is a viable option for pediatric choledocholithiasis. To optimize outcomes, further multicenter studies and improved pediatric training are recommended.
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