Exploring the association between weight-adjusted-waist index and overactive bladder: A population-based study.

Area of Science:

• Urology
• Public Health
• Metabolic Syndrome

Background:

• Obesity is a known risk factor for overactive bladder (OAB).
• Traditional anthropometric measures like BMI and waist circumference have limitations in assessing central obesity.
• The weight-adjusted-waist index (WWI) may offer a more precise assessment of central obesity.

Purpose of the Study:

• To investigate the association between the weight-adjusted-waist index (WWI) and the risk of overactive bladder (OAB).
• To compare the predictive ability of WWI against traditional anthropometric measures for OAB risk.

Main Methods:

• Multivariate logistic regression and restricted cubic splines were used to analyze the WWI-OAB relationship.
• Subgroup interaction analyses were performed to ensure result stability.
• Receiver operating characteristic (ROC) curves evaluated the predictive performance of WWI, BMI, and waist circumference.

Main Results:

• A significant positive association was found between WWI and OAB risk.
• Each 1-unit increase in WWI correlated with a 26% higher risk of OAB, even after adjusting for confounders.
• WWI demonstrated superior predictive power for OAB compared to BMI and waist circumference (AUC = 0.669).

Conclusions:

• Increased WWI is significantly associated with an elevated risk of overactive bladder (OAB).
• WWI serves as a more effective anthropometric indicator for assessing OAB risk than traditional measures.