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Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
11:58

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms

Published on: August 11, 2015

Intracranial mycotic aneurysms in pediatric patients: A systematic review

Hisan Alhafez1, Owais Mohammad Ahmad2, Mariam Kananyan3

  • 1Faculty of Medicine, University of Debrecen, Debrecen, Hungary.

Surgical Neurology International
|May 12, 2026
PubMed
Abstract

Insights

Pediatric intracranial mycotic aneurysms (IMAs) often present acutely. While antibiotics are crucial, endovascular and surgical treatments offer more effective aneurysm exclusion for better outcomes in children.

Area of Science:

  • Neurology
  • Vascular Surgery
  • Pediatric Medicine

Background:

  • Intracranial mycotic aneurysms (IMAs) are rare and dangerous vascular issues in children.
  • Their varied presentations necessitate tailored treatment strategies.

Purpose of the Study:

  • To systematically review the existing literature on pediatric IMAs.
  • To analyze management approaches and clinical outcomes for pediatric IMAs.

Main Methods:

  • Systematic review adhering to PRISMA 2020 guidelines.
  • Inclusion of studies with image-confirmed pediatric IMAs (≤18 years) and reported outcomes.
  • Data extraction and quality assessment using standardized criteria.

Main Results:

  • Most pediatric IMAs present acutely, with CT scans as the initial imaging.
  • Favorable outcomes were achieved in 61.1% (medical), 66.7% (endovascular), and 71.4% (surgical) management.
  • Complete aneurysm occlusion rates were 50% (medical), 100% (endovascular), and 81.8% (surgical).

Conclusions:

  • Pediatric IMAs often present acutely, frequently linked to infective endocarditis, demanding swift assessment.
  • Antimicrobial therapy is essential, but endovascular and surgical methods show higher rates of aneurysm exclusion.
  • Standardized reporting and multicenter registries are vital for advancing pediatric IMA surveillance and management.
Keywords:
EndovascularInfectious aneurysmNeuroimagingNeurosurgeryPediatricSystematic review

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