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Association between myopia severity and pupillary dynamics: a quantitative smartphone-based pupillometry study.

Pritam Dutta¹, Taksu Mech¹, Ritika Mudoi¹

¹Ridley College of Optometry, Chandraprabha Eye Hospital, Jorhat, India.

Clinical & Experimental Optometry

|May 12, 2026

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Pupillary dynamics change with myopia severity, showing slower responses and smaller pupil sizes in higher myopia. Smartphone pupillometry offers a non-invasive way to measure these vision changes.

Area of Science:

Ophthalmology and optometry
Neuroscience
Biomedical engineering

Background:

Pupillary dynamics offer objective insights into autonomic and retinal function.
Myopia progression may influence pupillary mechanisms.
Smartphone-based pupillometry presents a non-invasive method to assess these alterations.

Purpose of the Study:

To investigate changes in static and dynamic pupillary parameters across different myopia severities.
To compare pupillary responses between emmetropes and individuals with low, moderate, and high myopia.

Main Methods:

A comparative study involving 160 participants (40 per group) aged 18-35 years.
Pupillary dynamics were recorded using the Reflex Pro smartphone application under standardized lighting.

Keywords:

Myopia pupil dynamics pupillometry reflex pro smartphone-based assessment

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Key parameters analyzed included latency, constriction velocity, constriction amplitude, and constriction time.

Main Results:

Significant alterations in pupillary dynamics were observed with increasing myopia severity.
Latency increased, while constriction velocity, maximum constriction speed, and amplitude decreased as myopia worsened.
High myopia exhibited prolonged constriction time and a trend towards larger pupil diameter compared to emmetropes.

Conclusions:

Pupillary dynamics are demonstrably affected by myopia severity.
Smartphone-based pupillometry is a viable non-invasive tool for assessing these changes.
Further longitudinal studies are needed to establish causality.