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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Drugs that Stabilize Microtubules01:15

Drugs that Stabilize Microtubules

Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the spindle apparatus for segregating the chromosomes. This makes them ideal targets for regulating dividing cells in tumors and malignant cancer cells. Microtubule stabilizing drugs help stabilize the microtubule formation and promote its polymerization. Paclitaxel was the first microtubule stabilizing agent used as anticancer drug in chemotherapy...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

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Related Experiment Video

Updated: May 13, 2026

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines
07:59

A Comprehensive Procedure to Evaluate the In Vivo Performance of Cancer Nanomedicines

Published on: March 4, 2017

Nanoparticles: An Emerging Hope in Cancer Therapy.

Shahid Sher1, Rosny Jean2, Zaman Khan3

  • 1Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611, USA.

Nanomaterials (Basel, Switzerland)
|May 12, 2026
PubMed
Summary

Nanoparticles offer targeted cancer therapy by delivering drugs directly to tumors, minimizing harm to healthy cells. This review explores nanoparticle applications for breast, prostate, and lung cancers, highlighting future therapeutic potential.

Keywords:
cancerdelivery mechanismsdrugsnanoparticlessynthesistherapy

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Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
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Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

Published on: May 22, 2020

Area of Science:

  • Oncology
  • Nanomedicine
  • Materials Science

Background:

  • Cancer poses a significant global health challenge with limitations in conventional therapies due to non-specific toxicity.
  • Nanoparticles (NPs) present a promising solution for targeted drug delivery, enhancing therapeutic efficacy and reducing side effects.
  • The development of novel nanocarriers is crucial for advancing cancer treatment strategies.

Purpose of the Study:

  • To review nanoparticle applications for prevalent cancers (breast, prostate, lung) in the US (2025).
  • To analyze NP synthesis methods, delivery mechanisms (EPR, ATR), and their role in cancer therapy.
  • To provide a comparative, cancer-specific perspective on NP platforms from research to clinical trials.

Main Methods:

  • Comprehensive literature review of NP synthesis, delivery mechanisms, and applications in breast, prostate, and lung cancers.
  • Analysis of current research and clinical trial data for NP-based cancer therapies.
  • Comparative evaluation of organic and inorganic NPs, including specific examples like gold, magnetic, and polymeric NPs.

Main Results:

  • Gold and magnetic NPs show potential for early breast cancer detection.
  • Polymeric NPs (PCL, PLA, PLGA) are effective carriers for lung cancer therapeutics.
  • Emerging NP formulations (e.g., BIND-014) and established examples (liposomal doxorubicin, albumin-bound paclitaxel) demonstrate clinical relevance.

Conclusions:

  • Nanotechnology offers a pathway to more effective and targeted cancer therapies.
  • NP platforms have demonstrated significant potential across various cancer types, from detection to treatment.
  • Further research and clinical translation are essential to realize the full potential of nanomedicine in oncology.