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Related Experiment Video

Updated: May 14, 2026

Vessel-sparing Excision and Primary Anastomosis

Vessel-sparing Excision and Primary Anastomosis

Published on: January 7, 2019

Bulkamid for Recurrent SUI After Suburethral Sling Revision: Single-Center Study.

Christina Sze¹, Carolina Martinez Fernandez², Maali LaFrance²

¹Department of Urology, University of Texas Southwestern Medical Center.

Urogynecology (Philadelphia, Pa.)

|May 12, 2026

Summary

This summary is machine-generated.

Bulkamid injections effectively treat recurrent stress urinary incontinence (SUI) after sling revision, particularly for isolated SUI. This minimally invasive option offers significant symptom improvement for many patients.

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Area of Science:

Urology
Female Pelvic Medicine and Reconstructive Surgery

Background:

Postoperative stress urinary incontinence (SUI) after suburethral sling revision is a common complication impacting quality of life.
Polyacrylamide hydrogel (PAHG), marketed as Bulkamid, presents a minimally invasive treatment option for recurrent SUI, though data in this specific patient group is limited.

Purpose of the Study:

To assess the safety and efficacy of Bulkamid injections for persistent or recurrent SUI following suburethral sling revision.
To identify factors influencing treatment response in patients undergoing Bulkamid injections for post-sling revision SUI.

Main Methods:

Retrospective, single-center study of 41 women treated with Bulkamid for SUI or stress-predominant mixed urinary incontinence (MUI) after sling revision (2019-2024).
Incontinence severity evaluated using pad usage, Urogenital Distress Inventory-6 (UDI-6), Incontinence Impact Questionnaire-7 (IIQ-7), and patient-reported outcomes.
Statistical analysis included nonparametric and categorical methods with significance set at P<0.05.

Main Results:

Median pad use decreased significantly post-injection (2 to 0, P=0.01).
UDI-6 scores improved significantly (median 66.7 to 44.4, P=0.005), with notable improvements in urinary frequency and pain.
Symptom improvement was significant for SUI only (P=0.016) but not for MUI (P=0.258).

Conclusions:

Bulkamid injection is a safe and effective minimally invasive treatment for recurrent SUI after suburethral sling revision.
Patients with isolated SUI and those receiving a single injection experienced the greatest benefit.
Mixed urinary incontinence or prior synthetic slings may be associated with reduced treatment efficacy.