Preoperative Diastolic Dysfunction and Perioperative Risk Factors as Predictors of New Onset Atrial Fibrillation in

Yan Efrata Sembiring1,2, Lyndon Darwin1,2, Achmad Lefi3,4

  • 1Universitas Airlangga Faculty of Medicine Department of Thoracic Cardiac and Vascular Surgery Surabaya Indonesia Department of Thoracic Cardiac and Vascular Surgery, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.

Insights

New-onset postoperative atrial fibrillation (POAF) after coronary artery bypass grafting (CABG) is common. This study found preoperative diastolic dysfunction does not predict POAF, but identified other key risk factors.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Electrophysiology

Background:

  • Postoperative atrial fibrillation (POAF) is a frequent complication after coronary artery bypass grafting (CABG).
  • The underlying mechanisms of POAF are not fully understood, but impaired diastolic function is suspected.
  • Identifying predictors of POAF is crucial for patient management and risk stratification.

Purpose of the Study:

  • To investigate preoperative diastolic dysfunction (DD) as a predictor of new-onset POAF in patients undergoing CABG.
  • To identify other associated factors that may predict new-onset POAF following CABG.

Main Methods:

  • Retrospective cohort study of 191 patients undergoing CABG between January 2018 and August 2022.
  • Preoperative diastolic dysfunction assessed via transthoracic echocardiogram.
  • New-onset POAF monitored using continuous electrocardiogram.

Main Results:

  • No significant difference in preoperative diastolic dysfunction was observed between patients with and without POAF (P = 0.72).
  • Independent predictors of new-onset POAF included left main coronary artery disease (LMCAD), in-stent restenosis (ISR) ≥ 70%, reduced ejection fraction (≤ 50%), and electrolyte imbalance.
  • Specific odds ratios and confidence intervals were reported for each identified predictor.

Conclusions:

  • Preoperative diastolic dysfunction is not a predictor of new-onset POAF in CABG patients.
  • Male sex, LMCAD, ISR ≥ 70%, reduced left ventricular ejection fraction, and postoperative electrolyte imbalance are significant predictors of POAF.
  • These findings can aid in identifying high-risk patients for POAF after CABG.
Abstract

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