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[Laboratory investigation of hemoglobinopathies (author's transl)]
Abstract:
The importance of the haemoglobinopathies, mainly thalassaemia, as a public health problem has been emphasized. The establishment of methods for detection and diagnosis of haemoglobinopathies is the major step in laboratories dedicated to screening anemias. Tables for the diagnosis of alpha and beta thalassaemia are proposed, the methods to identify abnormal haemoglobins are discussed and a map with the relative mobilities of 115 abnormal haemoglobins by electrophoresis in alkaline buffer is shown.