Related Experiment Video
Updated: May 14, 2026
06:42
Use of the Scissor-Type Knife During the Peroral Endoscopy Myotomy Procedure for the Treatment of Achalasia
Published on: March 3, 2023
POEM-based endoscopic myotomy for esophageal diverticulum: a case series study
Kehan Li1, Cheng Guo1, Bensong Duan1
1Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, No.150 Jimo Road, Pudong New District, Shanghai, 200120, People's Republic of China.
BMC Gastroenterology
|May 13, 2026
Summary
Peroral endoscopic myotomy (POEM) is a safe and effective endoscopic treatment for esophageal diverticulum (ED). This minimally invasive approach demonstrated successful outcomes across various ED subtypes, including Zenker diverticulum.
Area of Science:
- Gastroenterology
- Minimally Invasive Surgery
- Endoscopic Procedures
Background:
- Esophageal diverticulum (ED) management traditionally involves surgery.
- Peroral endoscopic myotomy (POEM) utilizes submucosal tunneling for minimally invasive treatment.
- Limited evidence exists on POEM's efficacy across diverse ED types.
Purpose of the Study:
- To evaluate the clinical efficacy and safety of POEM for esophageal diverticulum.
- To assess POEM's applicability in different ED subtypes.
- To investigate POEM in patients with concomitant achalasia.
Main Methods:
- Single-center retrospective case series.
- Included patients with ED undergoing POEM-based endoscopic myotomy (February 2019 - February 2023).
- Tailored POEM techniques were applied based on diverticulum type (e.g., D-POEM, z-POEM).
Main Results:
- Seven patients with epiphrenic, Zenker, and mid-esophageal diverticula were treated.
- All procedures were technically successful with varying operative times.
- Complete diverticulum flattening and no clinical recurrence observed during follow-up.
Conclusions:
- POEM-based endoscopic myotomy is a feasible, minimally invasive option for selected ED patients.
- Combined POEM and diverticular myotomy may be suitable for cases with achalasia.
- Further research is warranted to confirm long-term outcomes.
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