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Updated: May 14, 2026

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
14:57

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

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Calbindin-D28k deficiency mediates tau-driven hippocampal hyperexcitement and cognitive impairment

Yang Gao1,2, Xiaoqing Tao3, Yuying Wang4

  • 1Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, China. gaoyangbest@whu.edu.cn.

Translational Neurodegeneration
|May 13, 2026
PubMed
Abstract

Keywords:
Alzheimer's diseaseCalbindin-D28kCalcium homeostasisCognitive impairmentTau hyperphosphorylationTemporal lobe epilepsy

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