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Published on: June 20, 2018
Diagnostic Approaches and Surgical Outcomes in Nasal Valve Dysfunction: A Systematic Review
Mahmoud Daoud1,2, Luana-Maria Gherasie1,3, Maria Louise Fufezan4
1Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Nasal valve dysfunction (NVD) diagnosis requires multiple methods, and both surgical and minimally invasive treatments significantly improve nasal breathing. Further research needs standardized diagnostics and comparative trials for NVD.
Area of Science:
- Otolaryngology
- Rhinology
- Medical Diagnostics
Background:
- Nasal valve dysfunction (NVD) is a frequent cause of nasal airway obstruction impacting quality of life.
- Current diagnostic standards for NVD are not universally accepted, and management strategies are debated.
- Existing evidence on diagnostic tools and treatment outcomes for NVD is fragmented.
Purpose of the Study:
- To systematically review and meta-analyze current evidence on diagnostic approaches for NVD.
- To evaluate the effectiveness of various treatment outcomes for NVD.
- To identify gaps in the evidence and suggest future research directions.
Main Methods:
- Systematic literature search of PubMed/MEDLINE, Embase, and Cochrane Library (1990-2026).
- Inclusion of RCTs, comparative studies, cohort studies, and case series (≥10 patients).
- Narrative synthesis of diagnostic data and meta-analysis of treatment outcomes (NOSE score).
Main Results:
- Seventy-two studies (15 diagnostic, 57 treatment) were included.
- Objective airflow measurements (rhinomanometry, peak nasal inspiratory flow) are more reliable than clinical maneuvers.
- Both surgical and minimally invasive interventions significantly improve nasal breathing (40-55 point NOSE score reduction), but direct comparison is limited by heterogeneity.
Conclusions:
- A multimodal diagnostic approach combining clinical assessment, symptom scores, and objective testing is recommended for NVD.
- Appropriately indicated surgical and minimally invasive treatments offer substantial symptom relief for NVD.
- The predominance of observational data highlights the need for standardized diagnostics and robust comparative trials in NVD research.
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