Electrospun Cellulose Acetate Nanofibers for Healthcare Products: Towards Sensing Pads for Endometriosis

The need for reliable preventive medicine tools is growing, especially for diseases with long diagnostic delays, such as endometriosis, which can take several years to diagnose. In this context, cellulose acetate nanofibrous membranes were prepared via electrospinning, to create the absorbent core of a smart wearable in the form of a sanitary pad, intended to support electronic diagnostic devices. A multi-layered structure was opted for, with each layer acting in a specific way according to its position within the pad, regarding mainly absorbency and porosity. The membranes were ultralight and highly absorbent, with single membranes showing an absorbency of 20-70 times their initial weight, and multi-layered membranes 15-30 times. Morphological evaluation of the pad was used as the basis for the optimization of the fabrication parameters, while liquid absorption capacity confirmed the pad's high absorbency. Additionally, chemical and toxicological assessments indicated in vitro biocompatibility of the pad. The potential of the electrospinning process in the fabrication of menstrual hygiene pads is shown by these results. Future studies should focus on the integration of smart devices within the pad, as well as their functionality and effectiveness.