Related Experiment Video
Updated: May 14, 2026

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
Nutritional Status, Body Composition, and Frailty in Community-Dwelling and Institutionalized Albanian Older Adults:
Sadmira Gjergji1,2, Stefania Moramarco3, Angela Andreoli1,4
1Faculty of Medicine, Catholic University of Our Lady of Good Counsel, 1026 Tirana, Albania.
Abstract:
Background: Albania has undergone a rapid demographic transition characterized by pronounced population aging. Comprehensive geriatric assessment-functional performance, validated nutritional screening tools, and systematic evaluation of morbidities-is essential for accurately characterizing frailty and identifying the risk of malnutrition in its early stages. The objective of the present study was to improve the assessment of the health status of Albanian older adults, both community-dwelling and residing in long-term care facilities, by addressing both functional and nutritional components. Methods: This observational study included Albanian older adults aged ≥ 65 years, both institutionalized and community-dwelling. Frailty and nutritional status were assessed using validated questionnaires (Grauer Geriatric Functional Evaluation and Mini Nutritional Assessment-MNA), alongside body composition analysis performed by bioelectrical impedance analysis (BIA). Results: Data for 123 older adults were analyzed (56.9% female; mean age 71.3 ± 7.4 years; 54.5% institutionalized vs. 45.5% community-dwelling). A high prevalence of frailty and multimorbidity was observed, particularly among institutionalized older adults. With regard to nutritional status, marked age-related differences were identified among females, with a pronounced deterioration in those aged over 75 years. Body-composition-derived parameters identified a substantially higher proportion of individuals at risk of malnutrition compared with other conventional anthropometric measures. Low body cell mass index (BCMI) and institutionalization were the factors with the strongest independent associations with frailty (AOR 5.02, 95% CI 1.69-14.87, p = 0.004, and AOR 5.71, 95% CI 1.76-18.54, p = 0.004, respectively), while low BCMI was the only variable associated with an increased risk of malnutrition (AOR 4.88, 95% CI 1.78-13.40, p = 0.002). Conclusions: These exploratory findings suggest that incorporating body composition parameters into geriatric assessment may provide complementary information alongside traditional screening tools to support the development of targeted preventive and therapeutic strategies.
Related Concept Videos
Development of Human Microbiota
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Pharmacodynamics in Geriatric Patients: Effects of Age
Drug Dosing: Geriatric Patients
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
