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Published on: January 20, 2023
Diffuse hypertrophic obstructive cardiomyopathy complicated by apical ventricular aneurysm and excessive left
Ying Li1,2, Na Jia2, Xinyue Li3
1Peking University Fifth School of Clinical Medicine, Beijing, China.
None:
This article reports a rare case of diffuse hypertrophic obstructive cardiomyopathy complicated with left ventricular apical aneurysm and excessive trabeculation. Genetic testing of the patient revealed a heterozygous variant of the MYBPC3 gene (c.3343G> A: p.Val1115Ile). Despite optimal medical therapy and implantable cardioverter-defibrillator (ICD) implantation, the patient developed progressive cardiac dysfunction and recurrent ICD shocks. We discuss the clinical course, genetic findings, and imaging features of this case.
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