Responsible chemistry for a changing world: IUPAC's guiding principles

The practice of chemistry is undergoing rapid transformation driven by innovation, convergence with other disciplines, and an urgent need to address global challenges from climate change to public health. At this critical juncture, the global chemistry community must embrace not only scientific excellence but also a shared commitment to ethical and responsible conduct that is aligned with world needs. Despite the existence of important national and sectoral ethical frameworks, their fragmented application has left a gap in establishing a truly global, inclusive, and actionable reference point for responsible chemistry. In response to this need, the International Union of Pure and Applied Chemistry (IUPAC) has developed and committed to propagating worldwide a set of guiding principles for the responsible practice of chemistry. These principles, developed by chemists for the profession of chemistry, provide a unifying ethical foundation and practical pathways to employ responsible innovation across chemistry research, education, and industry worldwide. These principles aim to provide a common ethical foundation for responsible chemistry worldwide-across sectors, generations, and locations. By aligning scientific excellence with societal well-being and environmental stewardship, these principles offer chemists and institutions tools to foster trust, accountability, and global collaboration.