Related Experiment Video
Updated: May 14, 2026

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
Published on: July 10, 2014
Etch-Bleach-Seal Technique in Managing Enamel Hypomineralization: A Case Report With Narrative Literature Review
Matine Gharavi1, Sara Tavassoli-Hojjati1, Zahra Abdolahpour1
1Department of Pediatric, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran, azad.ac.ir.
Background:
Molar incisor hypomineralization (MIH) opacities significantly affect pediatric patients' esthetics and psychosocial well-being. This case is unique as it demonstrates the clinical efficacy of a modified etch-bleach-seal protocol, utilizing a double application of sodium hypochlorite to address deep pigmentations where standard conservative approaches may be limited.
Objective:
This study is aimed at evaluating the clinical efficacy and existing literature supporting the etchâ€"bleachâ€"seal technique, a minimally invasive approach developed by Wright for managing enamel hypomineralizationâ€"related opacities.
Case Description:
A 10-year-old female presented with esthetic concerns regarding yellow-brown discoloration on her upper central incisors. After clinical and radiographic evaluations, a diagnosis of MIH was established. The patient was treated using the etch-bleach-seal technique, including phosphoric acid etching, sodium hypochlorite bleaching, and ICON resin sealing.
Outcomes:
Posttreatment, the patient showed significant improvement in enamel appearance. A follow-up session at 3 months led to further enhancement of esthetic results.
Conclusion:
The modified etch-bleach-seal protocol appears to be a promising conservative option for deep MIH opacities. However, as this represents a single clinical case, longitudinal studies are warranted to confirm its long-term durability and impact on enamel integrity.
