Peyronie's disease in Spain: a prospective study

Area of Science:

• Urology
• Andrology
• Men's Health

Background:

• Peyronie's disease (PD) research faces challenges due to patient heterogeneity.
• Variations exist in PD presentation, severity, and associated conditions.

Purpose of the Study:

• To detail clinical characteristics of Spanish PD patients.
• To analyze PD treatments used in clinical practice.
• To assess patient perceptions of treatment outcomes.

Main Methods:

• An observational, prospective multicenter cohort study included 601 men with PD.
• Data collected via medical history, physical examination, and validated questionnaires (IIEF-5, PDQ).
• Evaluated demographic data, plaque characteristics, curvature, and treatment modalities.

Main Results:

• Median patient age was 57 years; 41.6% were in the acute disease phase.
• Common non-surgical treatments included traction therapy (36.0%) and collagenase injections (29.3%).
• Penile plication (62.3%) was the most frequent surgical approach.

Conclusions:

• A wide array of PD treatments are employed in clinical practice, some lacking strong efficacy evidence.
• Improved understanding of PD is needed to develop optimal treatment protocols.
• Characterizing real-world PD patient profiles and satisfaction aids clinical decision-making.