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Predictive Effect of Perioperative Indexes on Scheduled Discharge of Lung Transplant Patients
Linfang Zeng1, Li Ke, Hong Feng
1>From theDepartment of Geriatric Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China; and the Department of Rehabilitation, Hefei, China.
Objectives:
Perioperative factors can influence planned discharge and survival prediction for lung transplant patients. In this study, we retrospectively analyzed perioperative clinical data of lung transplant recipients and assessed the predictive effects of relevant indexes on timely discharge of patients within 90 days post -transplant.
Materials And Methods:
We conducted a retrospective study on 81 lung transplant patients seen from March 1, 2017, to March 1, 2024, using data from the hospital information system. We used univariate and multi-variate logistic regression, ROC curve analysis, and Kaplan -Meier survival analysis to analyze perioperative indicators. To strengthen the robustness of our findings, we performed external validation.
Results:
Univariate logistic analysis showed that preoperative hemoglobin, albumin, blood loss, lactic acid, and postoperative hemoglobin were prognostic factors, whereas multivariate logistic analysis showed that postoperative lactic acid was an independent risk factor (P < .05 ). A negative correlation was shown between postoperative hemoglobin and lactate (r = -0.433, P < .001 ). External validation results provided additional confirmation of our study's findings.
Conclusions:
Further analysis and exploration with larger cohort studies are needed to enhance the generalizability and reliability of the findings that showed preoperative hemoglobin, albumin levels, blood loss, lactic acid, and postoperative hemoglobin were factors affecting prognosis and that postoperative lactic acid level was an independent risk factor discharge status.
