Related Experiment Video
Updated: May 14, 2026

Osteoarthritis Pain Model Induced by Intra-Articular Injection of Mono-Iodoacetate in Rats
Published on: May 20, 2020
Two new quaternary ammonium zwitterions from the noni juice and their anti-gout activities
Dong-Hui Zhang1,2,3, Yu-Qin Meng1,2,3, Xu-Hua Nong1,2,3
1Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Hainan Normal University, Haikou, Hainan, China.
Abstract:
Two new pyridinium zwitterions, (S)-3-phenyl-2(3-pyridinol-1-ium)-propanoate (1) and (S)-4-methyl-2-(3-pyridinol-1-ium)-pentanoate (2), together with five known alkaloids (3 - 7), were isolated and identified from noni juice, a health beverage made by fermenting the fruit of Morinda citrifolia L. Based on particular rotation data and electronic circular dichroism (ECD) computations, the absolute configurations of 1 and 2 were determined. The anti-gout properties of compounds 1-7 were assessed by measuring their capacity to restore cell viability in monosodium urate (MSU)-injured Human Umbilical Vein Endothelial Cells (HUVECs). These findings provide references for the analysis of pharmacologically active ingredients in noni juice.
More Related Videos
07:36Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea
Published on: December 23, 2022
06:14Tuina Intervention in Sodium Monoiodoacetate Injection-Induced Rat Model of Knee Osteoarthritis
Published on: January 12, 2024
Related Concept Videos
2° Amines to N-Nitrosamines: Reaction with NaNO2
Antihypertensive Drugs: Action of Diuretics
Nomenclature of Secondary and Tertiary Amines
Qualitative Analysis
For instance, group IV...
1° Amines to Diazonium or Aryldiazonium Salts: Diazotization with NaNO2 Overview
The nitrous acid is unstable. Hence, it is formed in situ from a solution of sodium nitrite and cold aqueous acids such as hydrochloric or sulfuric acid. In an acidic solution, the –OH group of nitrous acid undergoes protonation to give oxonium ion, followed by water loss...
Aryldiazonium Salts to Azo Dyes: Diazo Coupling