Related Experiment Video
Updated: May 14, 2026
Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Simplified UNICORN for Transcatheter Aortic Valve Replacement
Raviteja R Guddeti1, Janelle Muuse1, Santiago Garcia1
1The Carl and Edyth Lindner Research Center, The Christ Hospital, Cincinnati, Ohio, USA.
Objective:
The UNICORN (undermining iatrogenic coronary obstruction with radiofrequency needle) technique represents an emerging leaflet modification strategy for patients undergoing transcatheter aortic valve replacement (TAVR) at risk for coronary obstruction. We describe a simplified UNICORN procedure in patients undergoing valve-in-valve and native TAVR.
Key Steps:
This approach employs radiofrequency energy to traverse the base of the prosthetic aortic leaflet, followed by serial balloon inflations to create a large fenestration and subsequent transcatheter heart valve deployment, removing the risk of leaflet obstruction.
Potential Pitfalls:
Technical challenges include severely calcified leaflets that impede balloon advancement, the potential for leaflet fragment embolization with resultant coronary artery occlusion, and acute aortic insufficiency after balloon laceration.
Take-Home Message:
Compared with BASILICA (bioprosthetic aortic scallop intentional laceration to prevent iatrogenic coronary artery obstruction), UNICORN offers potential advantages, including enhanced leaflet tissue displacement and procedure simplification, minimizing the need for wire exchanges and snare retrieval maneuvers.
