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Dehydroepiandrosterone (DHEA) as a tool for conservation.

H Bobby Fokidis1

  • 1Department of Biology, Rollins College, 1000 Holt Avenue, Winter Park, FL, 32789-4499, USA. hfokidis@rollins.edu.

Environmental Monitoring and Assessment
|May 13, 2026
PubMed
Summary

Dehydroepiandrosterone (DHEA) shows potential as a wildlife conservation biomarker. Monitoring DHEA levels can reveal physiological resilience and inform conservation strategies.

Keywords:
Conservation physiologyEndocrine biomarkersEnvironmental adaptationHormoneStress responseWildlife reproductive health

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Area of Science:

  • Endocrinology
  • Conservation Physiology
  • Wildlife Biology

Background:

  • Dehydroepiandrosterone (DHEA) is a vital vertebrate steroid hormone.
  • DHEA influences stress, immunity, and reproductive functions, complementing glucocorticoid responses.
  • It offers insights into physiological resilience beyond just stress exposure.

Purpose of the Study:

  • To review the potential of DHEA as an endocrine tool in wildlife conservation.
  • To synthesize existing research on DHEA measurement and application in ecological contexts.
  • To identify challenges and future research directions for integrating DHEA into conservation physiology.

Main Methods:

  • Literature review synthesizing evidence across various taxa.
  • Assessment of DHEA measurement techniques and interpretation in ecological settings.
  • Analysis of DHEA's application in wildlife conservation studies.

Main Results:

  • DHEA monitoring can provide insights into adaptive capacity in wildlife.
  • Existing research highlights methodological challenges and taxonomic gaps in DHEA studies.
  • DHEA is an underutilized but promising biomarker for conservation.

Conclusions:

  • DHEA monitoring offers a valuable approach for assessing wildlife health and resilience.
  • Further research is needed to overcome methodological hurdles and expand taxonomic coverage.
  • Integrating DHEA into conservation physiology can significantly inform management decisions.