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Teaching artificial intelligence through drug-drug interaction clustering analysis: Integrating project-based
Ji Lv1, Guixia Liu2,3, Changjun Zhou1
1School of Computer Science and Technology, Zhejiang Normal University, Jinhua, China.
Plos Computational Biology
|May 13, 2026
Summary
This study introduces a project-based artificial intelligence (AI) course for non-computing undergraduates, using large language models (LLMs) to aid programming and analysis. The innovative approach enhances problem-solving skills and student engagement in AI research.
Area of Science:
- Educational Technology
- Artificial Intelligence in Education
- Computational Science
Background:
- Artificial intelligence (AI) is increasingly integrated into daily life and scientific research.
- Existing AI education often targets computer science majors, limiting access for undergraduates from non-computing backgrounds.
- A need exists for accessible AI instruction for early-stage undergraduates from diverse academic fields.
Purpose of the Study:
- To develop and evaluate an AI course for non-computing undergraduates.
- To integrate project-based learning (PBL) with large language models (LLMs) for AI education.
- To provide a framework for using LLMs as assistive tools in an undergraduate AI curriculum.
Main Methods:
- Designed a project-based AI course centered on drug-drug interaction network clustering analysis.
- Developed four progressive assignments utilizing LLMs to support programming, data analysis, and interpretation.
- Students engaged in a full data science workflow without requiring prior pharmacology or programming knowledge.
Main Results:
- Preliminary feedback indicates the course enhances problem-solving abilities.
- The project-based approach with LLM integration significantly increases student engagement.
- The curriculum successfully supports students through data curation, algorithm implementation, and result evaluation.
Conclusions:
- The study presents a viable framework for integrating LLMs into PBL for AI education.
- This teaching model is valuable for educators aiming to create or enhance AI courses for diverse student populations.
- The approach demonstrates the potential of LLMs to democratize AI education and foster interdisciplinary learning.