Related Experiment Video

Updated: May 15, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Long-term health outcomes of pediatric obstructive sleep apnea: A 10-year multicenter cohort study

Jui-Ju Tseng1, Jing-Jie Wang2, Ming-Chih Lin3

  • 1Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Hsinchu, Taiwan; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan; Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan.

Sleep Medicine
|May 13, 2026
PubMed

Insights

Pediatric obstructive sleep apnea (OSA) is linked to persistent health issues in children, including growth problems and ADHD. Adenotonsillectomy may reduce these risks, highlighting the importance of early diagnosis.

Area of Science:

  • Pediatric Health
  • Sleep Medicine
  • Child Development

Background:

  • Pediatric obstructive sleep apnea (OSA) is a growing concern with potential long-term health implications.
  • Understanding the multifaceted impact of OSA on child development is crucial for effective intervention.

Purpose of the Study:

  • To investigate the long-term associations between pediatric obstructive sleep apnea (OSA) and various child health domains.
  • To examine if surgical treatment, specifically adenotonsillectomy, influences these long-term outcomes.

Main Methods:

  • A retrospective cohort study followed children aged 2-18 with newly diagnosed OSA for up to 10 years.
  • Three groups were analyzed: non-surgically treated OSA, surgically treated OSA (adenotonsillectomy), and age-matched healthy controls.
  • Outcomes assessed included growth failure, developmental delays, obesity, precocious puberty, and ADHD, using propensity score matching and Cox models.

Main Results:

  • Children with non-surgically treated OSA showed significantly higher risks for growth failure, developmental delays, obesity, precocious puberty, and ADHD.
  • These risks were evident early and persisted throughout the follow-up period.
  • Adenotonsillectomy was associated with reduced risks of growth failure, developmental delays, and ADHD, but not obesity or precocious puberty.

Conclusions:

  • Pediatric OSA is associated with sustained adverse health outcomes across multiple domains.
  • Adenotonsillectomy may mitigate some of the growth, developmental, and neurobehavioral consequences of pediatric OSA.
  • Early identification and management of pediatric OSA are vital for improving long-term child health outcomes.
Abstract

Keywords:
AdenotonsillectomyAttention-deficit/hyperactivity disorderChild developmentLong-term outcomesObesityObstructive sleep apnea

More Related Videos

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders05:34

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders

Published on: August 18, 2023

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease04:53

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
Longitudinal Studies01:26

Longitudinal Studies

Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...