Related Experiment Video

Updated: May 15, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

MTMR4 variants have opposite gene-specific impact on life-threatening arrhythmic risk in type 1 and 2 long QT

Peter J Schwartz1, Annika Winbo2,3, Luca Sala1,4

  • 1Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano, Via Pier Lombardo, 22, Milan 20135, Italy.

European Heart Journal
|May 13, 2026
PubMed
Abstract

Keywords:
MTMR4ArrhythmiasInduced pluripotent stem cell-derived cardiomyocytesLong QT syndromeNEDD4LSudden cardiac death

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