Visual function comparison of a non-diffractive extended depth-of-focus and an enhanced monofocal intraocular lens...

This study compared the clinical outcomes and optical characteristics of the TECNIS Eyhance (EH; Johnson & Johnson Vision, Santa Ana, CA, USA) enhanced monofocal and the TECNIS PureSee (PS; Johnson & Johnson Vision) non-diffractive extended-depth-of-focus intraocular lenses (IOLs) sharing the same platform. In this retrospective analysis of real-world data, 69 eyes from 49 patients (EH: 35 eyes; PS: 34 eyes) were evaluated for visual acuity (VA) at distance, intermediate, and near ranges, alongside monocular defocus curves at 3-months postoperatively. To ensure a fair comparison and optimize intermediate vision, a consistent postoperative target refraction of -0.20 to -0.30 D was set for all eyes. Generalized estimating equations accounted for intra-subject correlations. At 3-months, both IOLs provided comparable excellent distance vision and refractive predictability without significant intergroup differences in prediction error (p = .846) or mean absolute error (p = .833). However, the PS IOL delivered significantly better uncorrected intermediate (0.16 vs. 0.23 logMAR; p < .001) and near VA (0.32 vs. 0.40 logMAR; p < .001) than the EH IOL. In conclusion, while both IOLs offer excellent distance vision and refractive stability, the non-diffractive PS IOL provides superior intermediate and near visual performance compared to the EH IOL.