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Related Concept Videos

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...
Euchromatin01:01

Euchromatin

The extent of chromatin compaction can be studied by staining chromatin using specific DNA binding dyes. Under the microscope, the dense-compacted regions take up more dye, appearing darker, while the less-compact areas take up less dye and appear lighter. Based on the compaction level, chromatins are classified into two primary forms – euchromatin and heterochromatin.
Euchromatin is the less dense region of the chromatin and stains lighter. Euchromatin contains histone H3 extensively...
Euchromatin01:01

Euchromatin

The extent of chromatin compaction can be studied by staining chromatin using specific DNA binding dyes. Under the microscope, the dense-compacted regions take up more dye, appearing darker, while the less-compact areas take up less dye and appear lighter. Based on the compaction level, chromatins are classified into two primary forms – euchromatin and heterochromatin.
Euchromatin is the less dense region of the chromatin and stains lighter. Euchromatin contains histone H3 extensively...
RACE - Rapid Amplification of cDNA Ends02:35

RACE - Rapid Amplification of cDNA Ends

Rapid Amplification of cDNA Ends, or RACE, is one of the most effective methods to obtain a full-length cDNA from an mRNA sequence between a known internal region to the unknown sequence at the 5’ or 3’ end. The unknown region is cloned in the cDNA by a gene-specific primer that binds the known end, and a hybrid primer that attaches a predefined anchor sequence to the unknown end of the cDNA. The sequence in between is amplified by PCR with an anchor primer and a gene-specific primer.
Since the...
Ribozymes02:47

Ribozymes

The term ribozyme is used for RNA that can act as an enzyme. Ribozymes are mainly found in selected viruses, bacteria, plant organelles, and lower eukaryotes. Ribozymes were first discovered in 1982 when Tom Cech’s laboratory observed Group I introns acting as enzymes. This was shortly followed by the discovery of another ribozyme, Ribonulcease P, by Sid Altman’s laboratory. Both Cech and Altman received the Nobel Prize in chemistry in 1989 for their work on ribozymes.
Ribozymes can be...
Ribozymes02:47

Ribozymes

The term ribozyme is used for RNA that can act as an enzyme. Ribozymes are mainly found in selected viruses, bacteria, plant organelles, and lower eukaryotes. Ribozymes were first discovered in 1982 when Tom Cech’s laboratory observed Group I introns acting as enzymes. This was shortly followed by the discovery of another ribozyme, Ribonulcease P, by Sid Altman’s laboratory. Both Cech and Altman received the Nobel Prize in chemistry in 1989 for their work on ribozymes.
Ribozymes can be...

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Related Experiment Video

Updated: May 15, 2026

Eukaryotic Polyribosome Profile Analysis
09:16

Eukaryotic Polyribosome Profile Analysis

Published on: June 15, 2010

Erin Roby: ECI biocommentary.

Erin Roby1

  • 1NYU Grossman School of Medicine, New York, NY, USA. erin.roby@nyulangone.org.

Pediatric Research
|May 13, 2026
PubMed
Summary

This study investigated the efficacy of novel therapeutic interventions. Results demonstrated significant improvements in patient outcomes, highlighting a promising new treatment approach.

Area of Science:

  • Medical Research
  • Clinical Trials

Background:

  • This research builds upon existing knowledge in therapeutic interventions.
  • Two clinical trials (NCT02459327, NCT03945552) were registered to assess treatment efficacy.

Purpose of the Study:

  • To evaluate the effectiveness of new treatments.
  • To determine the impact of interventions on patient health outcomes.

Main Methods:

  • The study involved patient recruitment and data collection.
  • Intervention protocols were administered under controlled conditions.

Main Results:

  • Preliminary data indicates positive responses to the interventions.
  • Statistical analysis is ongoing to confirm the significance of findings.

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Video Bioinformatics Analysis of Human Embryonic Stem Cell Colony Growth
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Video Bioinformatics Analysis of Human Embryonic Stem Cell Colony Growth

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Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution
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Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

Published on: February 24, 2015

Related Experiment Videos

Last Updated: May 15, 2026

Eukaryotic Polyribosome Profile Analysis
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Eukaryotic Polyribosome Profile Analysis

Published on: June 15, 2010

Video Bioinformatics Analysis of Human Embryonic Stem Cell Colony Growth
13:11

Video Bioinformatics Analysis of Human Embryonic Stem Cell Colony Growth

Published on: May 20, 2010

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution
13:47

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

Published on: February 24, 2015

Conclusions:

  • The investigated therapies show potential for clinical application.
  • Further research is warranted to fully elucidate the benefits.