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Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Allergic Reactions02:06

Allergic Reactions

Overview
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...

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Related Experiment Video

Updated: May 15, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Allergies and Lung Cancer: Exploring the Association with Allergic Rhinitis.

Mozhgan Moghtaderi1, Abbas Rezaianzadeh2, Seyed Hesamedin Nabavizadeh3

  • 1Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Mozhgan.moghtaderi96@gmail.com.

Iranian Journal of Allergy, Asthma, and Immunology
|May 14, 2026
PubMed
Summary

Allergic rhinitis (AR) shows a significant protective effect against lung cancer, unlike other allergies. Further research into AR

Keywords:
Allergic rhinitisAsthmaCancer immunologyHypersensitivityLung cancer

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Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
10:39

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

Published on: April 16, 2019

Related Experiment Videos

Last Updated: May 15, 2026

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
10:39

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

Published on: April 16, 2019

Area of Science:

  • Immunology
  • Oncology
  • Epidemiology

Background:

  • Allergies involve immune responses that may affect the tumor microenvironment.
  • The relationship between allergic conditions and lung cancer risk is not fully understood.

Purpose of the Study:

  • To investigate the potential association between allergic conditions and lung cancer risk.
  • To explore if specific allergic conditions have different impacts on lung cancer development.

Main Methods:

  • A case-control study involving 82 lung cancer patients and 82 healthy controls.
  • Data collected via questionnaires on asthma, allergic rhinitis (AR), food/drug allergies, and chronic urticaria.
  • Statistical analysis using t-tests and chi-square tests.

Main Results:

  • A significant inverse association was found between allergic rhinitis (AR) and lung cancer (OR=0.14).
  • No significant associations were observed for asthma, chronic urticaria, drug allergy, or food allergy.
  • The protective association of AR with lung cancer persisted after adjusting for demographic factors.

Conclusions:

  • Allergic rhinitis demonstrates a strong negative association with lung cancer, suggesting potential protective mechanisms.
  • Findings support allergy-cancer immunomodulatory interactions.
  • Further mechanistic studies on AR-specific pathways in oncogenesis are warranted.