Visualized Trends and Bibliometric Analysis in 3D Printing for Osteochondral Repair: A Comprehensive Research Study...

This study provides a comprehensive bibliometric analysis of the literature on 3D printing for osteochondral repair and regeneration, aiming to explore the current research landscape, key emerging topics, and future trends in this field. English-language publications on 3D printing technology and osteochondral repair, published between 2010 and 2024, were retrieved from the Web of Science Core Collection database. The search, conducted on May 1, 2024, followed a structured strategy. Bibliometric analysis was performed on 287 scholarly articles using the Bibliometrix package in R, VOSviewer, and CiteSpace. The study demonstrates a steady increase in global research activity, as reflected by the rising annual and cumulative publication rates in this field. China and the United States dominate in international collaboration, publication output, and funding investment. Collaborative networks between authors, institutions, and countries have played a pivotal role in advancing the development of 3D printing technology for osteochondral repair. The journal Biofabrication serves as the leading platform for disseminating research findings. Wu Chengtie is identified as the most prolific author, with "mesenchymal stem cell" emerging as the most prominent keyword. Research to date has focused on various types of mesenchymal stem cells, 3D printing technologies, and osteogenic differentiation, while future studies are anticipated to prioritize growth factor delivery, 3D bioprinting, and interface tissue engineering. This analysis highlights the advantages, limitations, and future prospects of osteochondral repair, a field at the intersection of medicine and engineering. The findings provide valuable insights to guide researchers in further advancing this rapidly emerging area.