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Related Concept Videos

Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...
X-ray Diffraction of Biological Samples01:10

X-ray Diffraction of Biological Samples

X-ray diffraction or XRD is an analytical tool that utilizes X-rays to study ordered structures such as crystalline organic and inorganic samples, polycrystalline materials, proteins, carbohydrates, and drugs.
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are  scattered by the electron clouds around the sample atoms. The  X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal crystal...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

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Related Experiment Video

Updated: May 15, 2026

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography
07:01

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

Published on: October 24, 2019

Data-driven deformation correction in X-ray spectro-tomography with implicit neural networks.

Ting Wang1, Zipei Yan2, Hongyi Pan3

  • 1Department of Statistics and Data Science, Southern University of Science and Technology, Shenzhen, China.

Patterns (New York, N.Y.)
|May 14, 2026
PubMed
Summary

CANet, a self-supervised neural network, corrects X-ray spectro-tomography image misalignments without external data. This method enhances nanoscale imaging for battery degradation analysis.

Keywords:
X-ray spectro-tomographycoordinate-based neural networkdeformation correctionimplicit neural representationsself-supervised learning

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Last Updated: May 15, 2026

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography
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Area of Science:

  • Materials Science
  • Nanotechnology
  • Spectroscopy

Background:

  • Full-field transmission X-ray microscopy with X-ray absorption near-edge structure spectroscopy (XANES) offers high-resolution, 3D chemical analysis.
  • Image deformations and misalignments in spectro-tomography limit reconstruction quality and downstream analysis.
  • This bottleneck restricts the application of X-ray spectro-tomography in complex scientific investigations.

Purpose of the Study:

  • To introduce a novel method for correcting image misalignments in X-ray spectro-tomography.
  • To enable accurate and efficient 3D morphological and compositional analysis.
  • To overcome limitations hindering the broader application of spectro-tomography.

Main Methods:

  • Development of CANet, a self-supervised coordinate-based neural network.
  • Implicit modeling of deformation fields for misalignment correction.
  • Learning a continuous mapping for unified registration across tomographic and spectral dimensions.

Main Results:

  • CANet effectively corrects misalignments in X-ray spectro-tomographic datasets.
  • Robust alignment and restoration of high-fidelity structural and chemical contrast.
  • Successful application to battery cathode particle datasets.

Conclusions:

  • CANet addresses a critical bottleneck in X-ray spectro-tomography.
  • The method facilitates the resolution of nanoscale degradation mechanisms in materials.
  • Enables non-destructive, high-resolution, chemically specific 3D analyses.